Chrismation is the Sacrament of the Holy Spirit, the Holy Spirit whom Christ Jesus sent (John 16:7). Jesus instructed his Apostles that they "will receive the power of the Holy Spirit" and called upon the Apostles to be His "witnesses to the ends of the earth" (Acts 1:8). At the Pentecost, the Apostles were filled with the Holy Spirit (Acts 2:1-4), and began to spread the Word of God. The Acts of the Apostles is often called the Gospel of the Holy Spirit.

The rite of Confirmation is anointing the forehead with chrism, together with the laying on of the minister's hands and the words, "Be sealed with the Gift of the Holy Spirit." The recipient receives the seven gifts of the Holy Spirit: wisdom, understanding, counsel, fortitude, knowledge, piety, and fear of the Lord (Isaiah 11:2-3). On occasion one may receive one or more of the charismatic gifts of the Spirit (1 Corinthians 12:7-11).

The ecclesial effect and sacramental grace of the Sacrament give the recipient the strength and character to witness for Jesus Christ. In the Roman rite this Sacrament is administered by the Bishop to children from age 7 to 18, but generally to adolescents, for example, to a graduating class of grade school children. Other key Scriptural sources for Confirmation are the following (See also Acts 1:4-5, 2:1-4, 2:38, 10:44-48)